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The article is dedicated to therapeutic efficacy of a combination of the antihypoxant bemithyl and the antidepressant pyrazidol in patients with asthenoneurotic and asthenovegetative syndromes after moderate isolated brain injury (BI). The combined therapy was shown to reduce long-term sequences of BI such as asthenic symptoms, stabilize both lipid peroxidation processes and serum antioxidative systems.

Antidepressive Agents/therapeutic use , Antioxidants/therapeutic use , Benzimidazoles/therapeutic use , Brain Injuries/complications , Carbazoles/therapeutic use , Neurocirculatory Asthenia/drug therapy , Adolescent , Adult , Drug Therapy, Combination , Female , Follow-Up Studies , Humans , Lipid Peroxidation/drug effects , Lipid Peroxidation/physiology , Male , Middle Aged , Neurocirculatory Asthenia/blood , Neurocirculatory Asthenia/etiology , Treatment Outcome

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